by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Neuroscience
It is poorly known how Aβ and tau accumulations associate at the spatiotemporal level in the in vivo human brain to impact cognitive changes in older adults prior to AD symptoms onset. In this study, we used a graph theory-based spatiotemporal analysis to characterize...
by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Neuroscience
Neurons typically generate action potentials at their axon initial segment based on the integration of synaptic inputs. In many neurons, the axon extends from the soma, equally weighting dendritic inputs. A notable exception is found in a subset of hippocampal...
by Clinical Neuropsychologist Online | Tuesday, February 13, 2024 | Neuroscience
Nature Neuroscience, Published online: 13 February 2024; doi:10.1038/s41593-024-01591-wAs Nature Neuroscience celebrates its 25th anniversary, we are having conversations with both established leaders in the field and those earlier in their careers to discuss how the...
by Clinical Neuropsychologist Online | Tuesday, February 13, 2024 | Neuroscience
Nature Neuroscience, Published online: 13 February 2024; doi:10.1038/s41593-024-01571-0Muller et al. demonstrate that reward signals recorded from the frontal cortex of nonhuman primates exhibit a population-based scheme for learning probability distributions over...
by Clinical Neuropsychologist Online | Monday, February 12, 2024 | Neuroscience
Nature Neuroscience, Published online: 12 February 2024; doi:10.1038/s41593-023-01562-7Wang et al. identify a molecularly defined tetra-synaptic pathway for olfaction-evoked innate fear and anxiety in mice. These findings reveal a forebrain-to-hindbrain neural...