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Gene replacement‐Alzheimer’s disease (GR‐AD): Modeling the genetics of human dementias in mice

by Clinical Neuropsychologist Online | Monday, February 12, 2024 | Dementia

Abstract INTRODUCTION Genetic studies conducted over the past four decades have provided us with a detailed catalog of genes that play critical roles in the etiology of Alzheimer’s disease (AD) and related dementias (ADRDs). Despite this progress, as a field we...

Tau accumulation and atrophy predict amyloid independent cognitive decline in aging

by Clinical Neuropsychologist Online | Friday, February 9, 2024 | Dementia

Abstract INTRODUCTION Amyloid beta (Aβ) and tau pathology are cross-sectionally associated with atrophy and cognitive decline in aging and Alzheimer’s disease (AD). METHODS We investigated relationships between concurrent longitudinal measures of Aβ (Pittsburgh...

Brain artery diameters and risk of dementia and stroke

by Clinical Neuropsychologist Online | Friday, February 9, 2024 | Dementia

Abstract INTRODUCTION We tested the association of brain artery diameters with dementia and stroke risk in three distinct population-based studies using conventional T2-weighted brain magnetic resonance imaging (MRI) images. METHODS We included 8420 adults > 40...

Reflections on co-production: Developing a dementia research funding application with a diverse lived experience group

by Clinical Neuropsychologist Online | Wednesday, February 7, 2024 | Dementia

Dementia, Volume 23, Issue 5, Page 709-723, July 2024. Introduction and Background to Study: Published work on dementia research co-production focuses on developing health and social care interventions. Less is written about practicalities and experiences of...

Assessment of dementia knowledge in Indian speech-language pathology students

by Clinical Neuropsychologist Online | Thursday, February 1, 2024 | Dementia

Dementia, Volume 23, Issue 5, Page 800-816, July 2024. ObjectivesSpeech-language pathologists (SLPs) have a crucial role in assisting individuals with dementia due to the communication and swallowing challenges associated with the disease. As the number of dementia...

Life story templates in dementia care: Ambiguous direction and purpose

by Clinical Neuropsychologist Online | Thursday, January 4, 2024 | Dementia

Dementia, Volume 23, Issue 5, Page 741-756, July 2024. BackgroundThe use of life stories in dementia care has been described as a way of seeing every person as an individual, looking beyond their dementia. Life stories have become synonymous with high-quality care,...
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