by Clinical Neuropsychologist | Monday, April 22, 2024 | Dementia
Dementia, Volume 23, Issue 6, Page 964-980, August 2024. ObjectiveThe main aim of this study was to evaluate the feasibility and acceptability of using a GPS tracker to mitigate the risks associated with wandering for people with dementia and those caring for them and...
by Clinical Neuropsychologist | Monday, April 22, 2024 | Dementia
Abstract INTRODUCTION We examined the efficacy of a multidomain intervention in preventing cognitive decline among Japanese older adults with mild cognitive impairment (MCI). METHODS Participants aged 65-85 years with MCI were randomized into intervention (management...
by Clinical Neuropsychologist | Monday, April 22, 2024 | Dementia
Abstract INTRODUCTION We investigate pathological correlates of plasma phosphorylated tau 181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) across a clinically diverse spectrum of neurodegenerative disease, including normal...
by Clinical Neuropsychologist | Monday, April 22, 2024 | Dementia
Abstract BACKGROUND Cortical microinfarcts (CMI) were attributed to cerebrovascular disease and cerebral amyloid angiopathy (CAA). CAA is frequent in Down syndrome (DS) while hypertension is rare, yet no studies have assessed CMI in DS. METHODS We included 195 adults...
by Clinical Neuropsychologist | Thursday, April 18, 2024 | Dementia
Abstract BACKGROUND Alzheimer’s disease (AD) prevalence increases with age, yet a small fraction of the population reaches ages > 100 years without cognitive decline. We studied the genetic factors associated with such resilience against AD. METHODS...
